MAIN RESEARCH PROJECTS

  • Project coordinator. The effects of "(±)-8-methoxy-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid ethyl ester" on viability, reactive radical production, insulin releasing and cytokine-mediated cell death in INS-1 cells. Supported by Gazi University Research Foundation No:01/2011-09. 2011-present.

  • Project coordinator. Development of Functional Nutrient, Dietary Supplement and OTC drug (pharmaceutical Formulations) from Olive leaf extracts. Supported by KOSGEB No:2011-0850. 2011-present.

  • Project coordinator. The effects of SMe1EC2 on glycoxidative stress markers and vascular reactivity on aging rats with or without diabetes. Supported by Gazi University Research Foundation No:01/2010-126. 2010-present.

  • Project co-coordinator. The effects of SMe1EC2 on endothelial functions, vascular reactivity and protein oxidations in diabetic rats as accelerated aging model. Supported by Ankara University Research Foundation No: 10B336002.2010-present

  • Project Leader and the coordinator of Turkish side. The role of oxidative stress in apoptosis and dysfunction of pancreatic beta cells: The potential protective effect of novel pyridoindole antioxidants. Supported by the   Scientific and Technological Research Council of Turkey (TUBITAK) and Slovak Academy of Sciences, SBAG-SLOVAK-4 No:108S239. 2008-present.

  • Project coordinator. The effects of low-dose chronic fluvastatine treatment on oxidative/nitrosative stres markers. Supported by Ankara University Research Foundation No: 2008-0803061. 2008-2010.

  • Project Coordinator. The effects of dietary restriction, exercise, orlistate and sibutramin on oxidative stress and antioxidation markers in obese patients. Supported by Gazi University Research Foundation No:01/2007-02. 2007-2010.

  • Project Leader and the coordinator. Research on effects of Olea europaea leaf extracts on protein-lipid oxidation, apoptosis signal transduction pathways and glucose stimulated insulin release in INS-1E pancreas beta    cell line", Supported by the European Science Foundation, COST Action B-35 (Lipid Peroxidation Associated Disease). Scientific and Technological Research Council of Turkey (TUBITAK) No:106S025. 2006-2010.

  • Project Leader and the coordinator. The vascular effects (in vivo and in vitro) of pyridoindole antioxidants on animal model of diabetes mellitus. Supported by Gazi University Research Foundation No:01/2004-42. 2004-2010.

  • Project Leader and the coordinator. Assesment of cardiovascular and Renovascular effects of antioxidant stobadine. Supported by Gazi University Research Foundation No:01/2003-50. 2003-2009.

  • Project Leader and the coordinator of Turkish side. Antioxidants and aldose reductase blockade in prevention of late diabetic complications: study on new pyridoindole derivatives. Supported by the Scientific and Technological Research Council of Turkey (TUBITAK) and Slovak Academy of Sciences, SBAG-SLOVAK-2 No:103S180. 2003-2007.

  • Project Leader and coordinator. Antioxidants and aldose reductase blockade in prevention of late diabetic complications: study on new pyridoindole derivatives", Supported by Turkish Scientific and Research Council (TUBITAK), No:SBAG-2397 (100S232), Ankara University Research Foundation No:2001-08-03-31 and Gazi University Research Foundation No:01-2003/50. 2001-2005.

  • Project Leader and coordinator. The role of some antioxidant compounds on the treatment of cardiovascular observed in experimental diabetes. Supported by Ankara University Research Foundation No:98-03-005. 1998-2000.

  • Principal Researcher. Effects of antioxidant treatment on the nerve dysfunction in STZ-diabetic rats; comparison with essential fatty acids. Supported by grants from the William Harvey Research Institute, Ono Pharmaceuticals and Scotia Pharmaceuticals. 1993-1994.

  • Researcher. Effects of aminoguanidine treatment on sciatic nerve Doppler flux and in vitro prostacycline release in experimental diabetes". Supported by grants from the William Harvey Research Institute and Ono Pharmaceuticals. 1993-1994

  • Researcher. The effects of essential fatty acids and anti-oxidants on sciatic nerve dysfunction in streptozotocin-diabetic rats" Supported by grants from the William Harvey Research Institute and Ono Pharmaceuticals. 1993-1994.

  • Principal researcher. The role of endothelial cells on the vascular reactivity in alloxan diabetic rats", Supported by Ankara University Research Foundation No:88-03-003. 1988-1990.


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